Trasylol (aprotinin) Injection, Bayer Pharmaceutical Division NDA 20-304/SE1-004 8/28/98 9/1/98 9/1/98 7/2/99 Trasylol Indication: Trasylol is indicated for prophylactic use to reduce perioperative blood loss and the need for blood transfusion in patients undergoing cardiopulmonary bypass in the course of coronary artery bypass graft surgery.