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CombinatoRx:
Neuromed pain drug may not get approval 7:48 AM 11/16/2009 Reuters CombinatoRx Inc which is merging with privately held Neuromed
Pharmaceuticals Inc said the US FDA has indicated that Neuromed's experimental pain drug Exalgo may not be
approved.
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Poniard
Shares Tumble As Lung Cancer Drug Doesn't Meet Goal 6:52 AM 11/16/2009
Wall Street Journal Poniard Pharmaceuticals Inc's picoplatin treatment for
small-cell lung cancer did not meet the primary overall survival endpoint in a late-stage study of effectiveness
in relapsed patients.
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Spherix
says diabetes drug shows promise 6:02 AM 11/16/2009 Reuters Spherix Inc said preliminary data from a late-stage trial of its experimental type 2
diabetes drug Naturlose showed a significant reduction in blood glucose levels. New drug application (NDA)
submission scheduled for 2010.
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Preliminary
Data Show Drug-Trial Failure For Genta 5:53 AM 11/16/2009 Wall Street Journal A late-stage trial of Genta Inc's injected Genasense in advanced melanoma
patients who haven't received chemotherapy failed to show improvement in disease control or progression-free
survival.
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Addex set for partner deal
after drug hits target 5:15 AM 11/16/2009 Reuters Addex Pharmaceuticalss lead drug candidate ADX10059 met its main target in a mid-stage
clinical trial in heartburn.
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Bristol-Myers
to Split Off Mead Johnson Nutrition Co. 4:10 AM 11/16/2009 Wall Street Journal Bristol-Myers Squibb Co is moving to split off its Mead Johnson Nutrition
Co nutritionals business in a deal valued at up to about $6.5 billion. Mead Johnson is best known for its
Enfamil infant formula.
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Niaspan tops Zetia in new setback for Merck drug 3:16 PM
11/15/2009 Reuters A small criticized study suggests that Abbott
Laboratories' Niaspan is more effective and safer than Merck & Co's Zetia as a secondary cholesterol treatment.
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Proposed
AstraZeneca Anticlotting Drug Better Than
Plavix 7:50 AM 11/15/2009 Wall Street
Journal AstraZeneca's experimental anticlotting drug ticagrelor was more effective than Plavix (clopidogrel)
when used before and after a procedure to open a blocked coronary artery in heart attack patients.
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FDA
questions caffeine in alcoholic beverages 2:19 PM 11/14/2009 Los Angeles Times Caffeine in drinks tends to mask the impairment produced by alcohol leading
to increased risk-taking and other serious alcohol-related problems.
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New
drug could boost women's libido 12:11 PM 11/14/2009 Los Angeles Times Flibanserin was originally developed by Boehringer Ingelheim as an
antidepressant. The drug does not lift the taker's spirits, but may increase the desire for sex thus raising the
partner's.
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U.S. FDA: Some
Genzyme drugs contaminated 11:42 AM 11/13/2009 Reuters The US FDA said that several Genzyme Corp products contained stainless steel fragments
and other foreign particles. Affected products include top-selling Cerezyme which treats Gaucher disease.
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Adeona gives positive
clinical data on arthritis
drug 10:06 AM 11/13/2009 Reuters Adeona
Pharmaceuticals Inc said its experimental rheumatoid arthritis drug dnaJP1 provided 20 percent improvement
during treatment.
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FDA
Extends Review of Cadence Drug 9:09 AM 11/13/2009 Wall Street Journal Cadence Pharmaceuticals said the US FDA delayed the review date on its
experimental Acetavance intravenous formulation of the pain reliever acetaminophen by three months.
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Cephalon, Barr settle
patent infringement suit 5:05 AM 11/13/2009 Reuters Cephalon will grant Barr a non-exclusive royalty-free right to market and sell a
generic version of Fentora (fentanyl) in the US effective in October 2018.
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A
New Cholesterol Study Puts Focus on Merck Drugs 4:45 AM 11/13/2009 New York Times A new small study will be released Monday. Previous studies reduced
sales of Merck drugs that may not work better than generic cholesterol lowering statin drugs.
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Antipsychotic
Drugs for Dementia To Be Curbed in UK 9:04 AM 11/12/2009 Bloomberg British dementia patients on antipsychotic drugs may experience as many as 1,800
deaths and 1,620 strokes a year. The government plans to curb overuse of the drugs including Eli Lilly’s
Zyprexa, Johnson & Johnson’s Risperdal, Bristol-Myers Squibb’s Abilify, AstraZeneca’s Seroquel, and Pfizer’s
Geodon.
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