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multiple system atrophy
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central nervous system, shy-drager syndrome, neurologic orthostatic hypotension, shy-mcgee-drager syndrome, parkinson's plus syndrome, multiple system atrophy, degenerative disorder characterized by the following, progressive damage, nervous system, low blood pressure, standing, difficulty urinating, abnormal breathing, sleep, muscle tremor, rigidity, slow movement, disrupted rem sleep patterns, multiple system atrophy, msa, rare degenerative condition, its symptoms, similar to those of parkinson's disease in that patients, move slowly, tremulous, shuffling gait, in msa there is more widespread neurologic damage, autonomic nervous system, portion, the nervous system that controls involuntary functions, progressive degeneration, the nervous system, damage to all parts, the nervous system, the brain, msa develops gradually, most often diagnosed in men older than 60, dizziness, fainting, arising, after standing still, impotence, loss of sweating of any part, loss of control of bowels, bladder, vision changes, decreased, blurred vision, muscle rigidity, stiffness, difficulty bending arms, legs, posture difficulties, unstable, stooped, slumped over, movement difficulties, loss of balance, gait, walking pattern, changes, shuffling, slow movements, difficulty beginning to walk, initiating any voluntary movement, small steps followed by the need to run to maintain balance, freezing of movement, the movement is stopped, unable to resume movement, muscle aches, pains, myalgia, tremors, present in varying degrees, not be present, occur at rest, at any time, become severe enough to interfere, tired, excited, stressed, finger-thumb rubbing, pill rolling tremor, action holding a cup, eating utensils, changes in facial expression, reduced ability to show facial expressions, "mask" appearance to face, staring, unable to close mouth, voice, speech changes, slow speaking, voice is low-volume, monotone, difficulty speaking, difficulty chewing, swallowing, loss of fine motor skills, difficulty writing, illegible, difficulty eating, activity that, small movements, frequent falls, mild decline in intellectual function, additional symptoms that associated, depression, confusion, dementia, seborrheic dermatitis, sleep-related breathing difficulties, sleep apnea, air passage obstruction accompanied by a harsh vibrating sound, perform the following, eye examination, reveal atrophy, the iris, paralysis of eye muscles, neuromuscular examination, abnormal reflexes, severe muscle wasting, atrophy, blood pressure measurement, reveal postural hypotension, drop in blood pressure associated, change in position, parkinsonian movements, tremor, rigidity, slow movements similar to parkinson's disease, common, no specific tests to confirm this disease, a neurologist, make the diagnosis, the history of symptoms, findings, physical examination, ruling out other causes, testing to help confirm the diagnosis, plasma norepinephrine levels, urine examination, norepinephrine breakdown products, urine catecholamines, mri of head to rule out other pathology, no specific abnormalities on imaging associated, msa, no cure, msa, no known means to slow progression, treatment is aimed at controlling symptoms postural hypotension, parkinsonian movements, anticholinergic medications, reduce early, mild tremors, levodopa, improve movement, balance, carbidopa, reduce the side effects of levodopa, make it work better, response to medications disappointing, many affected individuals respond poorly to treatment, anticholinergics, levodopa, medications that, treat low blood pressure, vasoconstrictors, midodrine, beta-blockers, mao inhibitors, vasopressin, 9-fluohydrocortisone, a pacemaker programmed to stimulate the heart to beat at a rapid rate, faster than 100 beats per minute, increase blood pressure, people, constipation, a high-fiber diet, laxatives, impotence treated, drugs that enhance erections, probable outcome is poor, progressive loss of mental, physical functions, general debilitation develops, early death is likely, rate of progression differs in every case, speed of decline, vary widely in individual patients, progressive loss of ability to walk, care, self, difficulty performing daily activities, injuries from falls/fainting, side effects of medications, develop symptoms of this disorder, have been diagnosed, msa, symptoms recur, progress, new symptoms appear, side effects of medications, involuntary movements, nausea/vomiting, dizziness, changes in alertness/behavior/mood, severe confusion, disorientation, delusional behavior, hallucinations, loss of mental functioning, the specific medication, side effects, consult, family member, condition deteriorates, point, unable to care, the person at home.
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