multiple myeloma…

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cryoglobulinemia, the fingers, immune system structures, antibodies, plasma cell dyscrasia, plasma cell myeloma, malignant plasmacytoma, plasmacytoma of bone, multiple myeloma, cancer, the plasma cells in bone marrow, multiple myeloma is characterized by the, excessive growth, malfunction, plasma cells, in the bone marrow, growth, extra plasma cells interferes, the production of red blood cells, white blood cells, platelets, anemia, susceptibility to infection, increased tendencies toward bleeding, the cancer cells grow, expand, in the bone marrow, cause pain, destruction, the bones, bones, in the spine, compression, the nerves, result causing numbness, paralysis, renal failure, kidney failure, frequent complication, excess calcium, in the blood that results from bone destruction, multiple myeloma mainly affects older adults, risk factors, unknown, disease is rare, 3 new cases per 100,000 people per year occur, in the us, bone, back pain, unexplained fractures, bleeding problems, increased susceptibility to infection, symptoms of anemia, tiredness, shortness of breath, fatigue, a bone marrow biopsy is performed, serum protein electrophoresis is abnormal, bone x-rays show fractures, hollowed out bone lesions, chemistry profile shows increased serum calcium, total protein, abnormal kidney function, complete blood count, cbc, reveals low hematocrit, anemia, low red blood cell count, rbc, low platelets, low white blood cell count, wbc, tests, bone lesion biopsy, t-lymphocyte count, serum globulin electrophoresis, quantitative immunoglobulins, nephelometry, serum immunoelectrophoresis, esr, febrile-cold agglutinins, cryoglobulins, blood differential, ionized calcium, protein in urine, urine immunofixation, urine immunoelectrophoresis, calcium in urine, bence-jones protein, quantitative, 24-hr urine protein, goal of treatment, relieve symptoms, chemotherapy, transplant rarely lead to permanent cure, complete remission is unusual, mild disease, whom the diagnosis is in doubt, observed, slow-developing form which takes years, it causes, disease advances, treatment is begun, chemotherapy, localized radiation therapy, relief of bone pain, treating a bone tumor useful, bone marrow transplantation in younger patients has been shown to increase disease-free, overall survival, has significant risks, several promising new treatments, thalidomide, proteosome inhibitors, arsenic trioxide, currently investigated in clinical trials, discuss participation, symptoms of high serum calcium levels, dehydration is avoided to help maintain proper kidney function, stress of illness eased by joining a support group whose members share common experiences, cancer, support group, average, median, survival of people, multiple myeloma, 3 years, depends on the patient's age, stage of disease, very aggressive, others take years to progress, discuss individual condition, renal failure, increased susceptibility to infection, pneumonia, paralysis from tumor, spinal cord compression, bone fractures, experience decreased urine output, have multiple myeloma, infection develops, numbness, loss of movement, loss of sensation develops.