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membranous nephropathy…

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kidney anatomy, membranous glomerulonephritis, membranous gn, extramembranous glomerulonephritis, glomerulonephritis, membranous, membranous nephropathy, kidney disorder resulting in disruption of kidney function, inflammation, the glomerulus, in the glomerular basement membrane, glomeruli, the inner structures, the kidney that include small capillaries surrounded by membranes, the blood is filtered to form urine, membranous nephropathy, thickening, the capillary wall, the glomerular basement membrane, deepest membrane, by immune complexes, the most common causes, nephrotic syndrome, most common presentation, appear, asymptomatic excretion of protein, in the urine, glomerular filtration rate, "speed" of blood purification, nearly normal, examination of sediment, in the urine unremarkable, oval fat bodies, hyaline, granular, fatty casts, membranous nephropathy a primary renal disease of uncertain origin, risks include systemic disorders hepatitis b, malaria, malignant solid tumors, non-hodgkin's lymphoma, systemic lupus erythematosus, syphilis, risks also include exposure to substances, medications, gold, mercury, penicillamine, trimethadione, skin-lightening creams, disorder occurs in approximately 2 out of 10,000 people, occur at any age but is more common after age 40, edema , swelling, in any area, generalized, foamy appearance of urine, weight gain, from fluid retention, poor appetite, urination, excessive at night, blood pressure, high, in many cases, no symptoms at, an examination nonspecific except foredema, a urinalysis, reveal protein, in the urine, blood, in the urine, hematuria, serum albumin low, blood lipid levels, increase, kidney biopsy confirms the diagnosis of membranous nephropathy, goal of treatment, minimize symptoms, slow the progression, medications, corticosteroids, immunosuppressive medications used, variable results, medications to treat symptoms, antihypertensive, diuretic medications, antibiotics needed to control infections, treatment of high blood cholesterol, triglyceride levels is recommended to reduce the development of atherosclerosis secondary to nephrotic syndrome  dietary limitation of cholesterol, saturated fats of only limited benefit, the high levels of cholesterol, triglyceride, overproduction by the liver rather than, excessive intake of fats, medications to reduce cholesterol, triglycerides recommended, individuals, at increased risk, thrombotic, clotting, events involving the lungs, pulmonary embolisms, legs, deep venous thromboses, dvts, therefore occasionally, prescribed warfarin, blood thinners, prevent these complications, high-protein diets, debatable value, in many patients, reducing the amount, protein, in the diet produces decrease in protein, in the urine, a moderate-protein diet, 1 gram of protein per kilogram of body weight per day, sodium in diet, salt, restricted to help control edema, vitamin d, replaced, nephrotic syndrome is chronic, did not respond to therapy, condition may go away, get worse, therapy, course, the disorder is highly variable, spontaneous remission, disease goes away, variable course of remissions, symptom-free periods, acute symptomatic episodes, 70-90% of patients, have some degree of irreversible kidney damage, 2-20 years, 20% progressing to end-stage renal disease, nephrotic syndrome, chronic renal failure, end-stage renal disease, renal vein thrombosis, pulmonary embolism, symptoms indicate membranous nephropathy present, symptoms worsen, persist, experience a decreased urine output, new symptom develops, prompt treatment of associated disorders, avoidance of associated substances, reduce risk.



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