lupus nephritis…

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male urinary system, nephritis, lupus, lupus glomerular disease, lupus nephritis, kidney disorder, complication of systemic lupus erythematosus, characterized by damage, glomerulus, progressive loss of kidney function, lupus nephritis is one complication of systemic lupus erythematosus, sle, autoimmune process of lupus, immune system produces antibodies, antinuclear antibody, against body components, complexes of these antibodies, complement accumulate, in the kidneys, result in an inflammatory response, lupus causes, various disorders, the internal structures, the kidney, interstitial nephritis, mesangial gn, membranous gn, membranoproliferative gn, diffuse proliferative gn, nephrotic syndrome, excessive protein excretion, progress rapidly to renal failure, progressive azotemia, accumulation of nitrogenous waste products, in the bloodstream, urinary abnormalities, protein, blood, in the urine, lupus nephritis affects approximately 3 out of 10,000 people, systemic lupus erythematosus, common in women 20-40 years old, runs in families, more common in blacks, related to other autoimmune disorders, rheumatoid arthritis, scleroderma, has been known to be triggered by pregnancy in children, sle, half, have some form, degree of kidney involvement, blood, in the urine, foamy appearance to urine, swelling of any area, elevated blood pressure, symptoms of sle, joint pain, joint swelling, joint redness, rash, commonly on the face but, occur on other areas, characteristic "butterfly" distribution, chest pain, sharp, stabbing, cough, sun sensitivity, fever, develop after exposure to sun, rash, develop after exposure to sun, fatigue, mouth ulcers, painless, neurologic changes, seizures, dementia, psychosis, examination indicates decreased kidney functioning, edema, indicate kidney failure, blood pressure high, abnormal sounds heard, the doctor listens, heart, lungs, indicating fluid overload, lupus nephritis, discovered, investigation, reduced kidney function, fewer than half of patients have other symptoms of sle, time of diagnosis of lupus nephritis, a urinalysis is abnormal, protein, casts, red blood cells present, in the urine, an ana titer is high, syphilis tests falsely positive, bun, creatinine, assess kidney functioning, a lupus erythematosus, le, cell test is positive, a kidney biopsy is indicated, not to diagnose lupus nephritis, what treatment is appropriate, the renal component of sle, a urine immunoglobulin light chain is elevated, tests, complement component 3, complement, goal of treatment is improvement of kidney function, corticosteroids, immunosuppressive medications, effective in reducing symptoms, whether high doses of corticosteroids, immunosuppressives, likely to be beneficial depends on the precise findings on kidney biopsy, dialysis necessary to control symptoms of acute, chronic renal failure, renal failure severe, require dialysis, no other symptoms of sle, a kidney transplant recommended to treat kidney failure resulting from lupus nephritis, diffuse proliferative lupus nephritis, one specific form, the disorder, sle, course is variable, exacerbations, acute episodes, remissions, symptom-free periods, cases of lupus nephritis, progress to chronic renal failure, over 80% of people, lupus nephritis severe, require dialysis, transplantation, survive, more than 5 years after treatment, lupus nephritis, recur, transplanted kidney, rarely leads to end stage renal disease, active lupus should not undergo transplantation, acute renal failure, chronic renal failure, end-stage renal disease, nephrotic syndrome, blood, in the urine, swelling, the body develops, have lupus nephritis, decreased urine output, no known prevention, lupus nephritis, harris ed, budd rc, genovese mc, firestein gs, sargent js, sledge cb, kelley's textbook of rheumatology, 7th ed, wb saunders, noble j, textbook of primary care medicine, 3rd ed, mosby, 2001.