gas gangrene…

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gas gangrene, gas gangrene, antibodies, tissue infection, clostridial, gangrene, gas, myonecrosis, clostridial infection of tissues, gas gangrene, severe form of gangrene, tissue death, clostridium perfringens, necrotizing subcutaneous infection, from group a streptococcus, staphlococcus aureus, vibrio vulnificus, cause similar infections, gas gangrene occurs, a result of infection by clostridium bacteria, under anaerobic, low oxygen, produce toxins that cause the tissue death, associated symptoms, gas gangrene is rare, 1,000 to 3,000 cases occurring, in the united states annually, gas gangrene generally occurs, site of trauma, a recent surgical wound, a third of cases occur spontaneously, patients who develop this disease spontaneously often have underlying vascular disease, atherosclerosis, hardening, the arteries, diabetes, colon cancer, onset of gas gangrene is sudden, dramatic, inflammation begins, site of infection, a pale-to-brownish-red, extremely painful tissue swelling, gas felt, in the tissue, a crackly sensation, the swollen area is pressed, the fingers, margins, the infected area expand so rapidly that changes, visible over a few minutes, involved tissue is completely destroyed, clostridium bacteria produce many different toxins, four of, alpha, beta, epsilon, iota, cause potentially fatal syndromes, cause tissue death, necrosis, destruction of blood, hemolysis, local decrease in circulation, vasoconstriction, leaking on the blood vessels, increased vascular permeability, toxins, the local tissue destruction, systemic symptoms, symptoms that occur throughout the body, systemic symptoms develop early, in the infection, consist of sweating, fever, anxiety, untreated, individual develops a shock -like syndrome, decreased blood pressure, hypotension, renal failure, coma, finally death, moderate to severe pain around a skin injury, progressive swelling around a skin injury, moderate to high fever, skin color initially pale, later dusky progressing to dark red, purple, vesicle formation, coalescent, combine into large blisters, blisters filled, brown-red fluid, drainage, tissues, foul-smelling brown-red, bloody fluid, serosanguineous discharge, increased heart rate, tachycardia, sweating, subcutaneous emphysema, air under the skin, begin suddenly, rapidly worsen, shock present, evidenced by general pallor, cold extremities, low blood pressure, rapid heart rate, air, in the tissues, crepitus, felt, infection involving the entire body, systemic toxicity, sepsis, yellow skin color associated, excessive breakdown of blood cells, jaundice, a gram stain of fluid, infected area, gram-positive rods, spore formation, bacterial types, a culture, grow the bacteria causing the infection, blood cultures, grow the infecting bacteria, an anaerobic tissue, fluid culture, reveal clostridium species, an x-ray, ct scan, mri, the area, gas, in the tissues, prompt surgical removal of dead, infected tissue, debridement, amputation of an arm, leg indicated to control the spread of infection, antibiotics, preferably penicillin-type, initially, given intravenously, a vein, analgesics required to control pain, hyperbaric oxygen has been tried, varying degrees of success, gas gangrene is progressive, lethal, immediate medical attention, disfiguring, disabling permanent tissue damage, jaundice, liver damage, kidney failure, spread of infection, sepsis, shock, stupor, delirium, coma, call heath care provider, signs of infection occur at any time around a skin wound, pain, swelling, redness, drainage of pus, blood, fever, similar symptoms, symptoms indicate gas gangrene, an emergency condition requiring immediate medical attention, clean any skin injury thoroughly, watch, signs of infection, redness, pain, drainage, swelling around a wound.