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bortezomib, bor-tez-oh-mib, belongs to the general group, medicines known as antineoplastics, treat multiple myeloma in patients who have received at least one treatment that has not helped, bortezomib interferes with the growth, cancer cells, which are then eventually destroyed by the body, the growth, normal body cells may also be affected by bortezomib, other effects will also occur, serious, reported to a physician, other effects may not be serious, some effects may not occur until months, years after the medicine is used, bortezomib is, administered only by, under the supervision, available, following dosage form
parenteral, injection, using the medicine, weighed against the good it will do, for bortezomib, allergic reaction to bortezomib, boron, mannitol, allergic to any other substances, foods, preservatives, dyes, there is a chance that this medicine, birth defects (Encyc) if, taken by the mother during pregnancy, studies in rats and rabbits, bortezomib causes birth defects (Encyc), fetus and other problems including miscarriage, needed in serious diseases, other situations that threaten the mother's life, have discussed these possible effects with a physician before receiving this medicine, before receiving bortezomib make sure a physician knows, pregnant, may become pregnant, best to use birth control to prevent pregnancy, receiving bortezomib, tell a physician right away if you think you have become pregnant while receiving bortezomib, when breast-feeding (Encyc), because bortezomib, serious side effects, breast-fed baby, when breast-feeding (Encyc), is generally not recommended, receiving this medicine, studies on this medicine, done only in adult patients, bortezomib in children with use in other age groups, an interaction might occur, change the dose, when you are taking bortezomib, amiodarone, cordarone, antivirals, stavudine, isoniazid, e.g, nydrazid, nitrofurantoin, macrodantin, macrobid, statins, lipitor, zocor, mevacor, with bortezomib may increase the chance, peripheral neuropathy, tingling, burning, numbness (Encyc), pain, in my hands and feet, antihypertensives, high blood pressure medicine, may increase the chances, low blood pressure, hypotension, certain medicines should not be used, an interaction might occur, change the dose, taking any other prescription, nonprescription, over-the-counter, otc] medicine, other medical problems, bortezomib, any other medical problems, dehydration, syncope, orthostatic/postural hypotension, heart disease (Encyc), bortezomib, heart problems worse, cause new heart problems, a physician will watch, side effect, kidney disease (Encyc), liver disease (Encyc), higher blood levels, bortezomib may result and a smaller dose, peripheral neuropathy, bortezomib may make the symptoms worse, cause new symptoms, tumor lysis syndrome, risk, bortezomib may increase my chance, getting this side effect, a physician will watch, side effect, bortezomib will be different for different patients, follow a physician's orders, the directions on the label, the average doses, bortezomib, any questions about the proper dose, bortezomib, for injection, dosage form, for treatment, multiple myeloma, patients without symptoms, with grade 1 symptoms, peripheral neuropathy, paresthesias and/or loss, reflexes without pain, function, 1.3 milligrams, per m twice weekly for two weeks, days 1, 4, 8, 11, followed by a 10 “day rest period, days 12 “21, for longer treatment, more than 8 cycles, bortezomib, taken on the regular schedule, a maintenance schedule, once a week for 4 weeks, days 1, 8, 15, 22, followed by a 13-day rest period, days 23 “35, at least 72 hours should elapse between consecutive dose, patients with grade 1 with pain, grade 2 symptoms, peripheral neuropathy, interfering with function, not with activities, daily living, 1 milligram, per m twice weekly for two weeks, days 1, 4, 8, 11, followed by a 10 “day rest period, days 12 “21, at least 72 hours should elapse between consecutive dose, patients with grade 2 with pain, grade 3 symptoms, peripheral neuropathy, interfering with activities, daily living, a physician will withhold therapy until toxicity resolves, when toxicity resolves a physician will reduce my dose to 0.7 mg/m once per week, patients with grade 4 symptoms, peripheral neuropathy, permanent sensory loss that interferes with function, a physician will discontinue therapy, a physician may decrease, dose for severe side effects excluding peripheral neuropathy, bortezomib is not usually recommended in children, missed dose discuss with a physician what to do
precautions, know the side effects, a physician check you at regular visits to make sure that this medicine is working properly, for unwanted effects, some people to become drowsy, dizzy, less alert than they are normally, before you drive, dizzy, not alert, vomiting and diarrhea, important to drink plenty, fluids, experience dizziness (Encyc), lightheadedness, contact a physician, could be symptoms, dehydration, not enough water, in my body, are diabetic and you take an oral antidiabetic medicine, should check my blood sugar level often and report any unusual changes to a physician, side effects, along with its needed effects, some unwanted effects, side effects may occur, may need medical attention, the way these medicines act on the body, there is a chance that they might cause other unwanted effects that may not occur until months, years after the medicine is used, discuss these possible effects with a physician,
check with a physician immediately, side effects occur, tarry stools (Encyc), bleeding gums, blood in urine (Encyc), stools, blurred vision (Encyc), body aches (Encyc), pain, burning, crawling, itching, numbness (Encyc), prickling, "pins and needles", tingling feelings, chest pain (Encyc), chills, confusion, faintness, lightheadedness when getting up from a lying, sitting position suddenly, cough, decreased urination, labored breathing, dry mouth, ear congestion, fainting, fever, headache, increase in heart rate, voice, lower back, side pain, nasal congestion, pale skin, painful, difficult urination (Encyc), painful blisters on trunk, pinpoint red spots on skin, rapid breathing, runny nose, shortness of breath, sneezing, sore throat, sunken eyes, sweating, tightness in chest, thirst, troubled breathing with exertion, wrinkled skin, ulcers, sores, white spots in mouth, unsteadiness, awkwardness, unusual bleeding, bruising, unusual tiredness (Encyc), weakness, weakness in arms, hands, legs, feet, wheezing, incidence not known, abdominal pain and tenderness, agitation, back pain, bloating, bruising, coma, constipation, coughing, vomiting blood, dark urine, deafness, dizziness (Encyc), dizziness, lightheadedness, especially when getting up from a lying, sitting position, drowsiness (Encyc), fast heartbeat, general tiredness and weakness, hallucinations, irritability, light-colored stools, mood, mental changes, pains in stomach, side, abdomen, possibly radiating to the back, persistent bleeding, oozing from puncture sites, mouth, nose, pounding, slow heartbeat, rectal bleeding, seizures, stiff neck, troubled breathing, upper right abdominal pain (Encyc), yellow eyes, skin, symptoms, overdose
if you think you, someone else, taken an overdose get emergency help at once, side effects may go away during treatment, body adjusts to the medicine, side effects continue, bothersome, acid, sour stomach (Encyc), back pain, belching, bone pain, diarrhea, difficulty in moving, difficulty having a bowel movement, fatigue, fear, nervousness, feeling unusually cold; shivering, heartburn, indigestion, itching skin, appetite, taste, change in taste, malaise, muscle cramps (Encyc), nausea, pain in joints, muscle pain, stiffness, pain in limb, rash, sleeplessness; trouble sleeping; unable to sleep, stomach discomfort, upset, pain, swelling, stomach pain, swollen joints (Encyc), vomiting,
other side effects,
additional information
once a medicine has been approved for marketing for a certain use, experience may show, also useful for other medical problems, this use is not included, product labeling, bortezomib is used in certain patients with the following medical conditions, mantle cell lymphoma
other than, information, there is no additional information relating to, side effects, use,
brand names, velcade
category
antineoplastic
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