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pegaspargase, peg-as-par-jase, belongs to the general group, medicines known as antineoplastics, treat some kinds, cancer, pegaspargase seems to interfere with the growth, cancer cells, which are eventually destroyed, the growth, normal body cells also, affected by pegaspargase, other effects also occur, serious, reported to a physician, before you begin treatment with pegaspargase, and a physician should talk about the good this medicine will do as well as the risks, using it, pegaspargase is, administered only by, under the immediate supervision, available, following dosage form parenteral, injection, for pegaspargase, allergic reaction to pegaspargase, pegaspargase has not been studied in pregnant women, animals, many cancer medicines, sterility that could be permanent, sterility has not been reported with pegaspargase, the possibility, this effect in humans should be kept in mind, cancer medicines may also cause birth defects ; therefore, use during pregnancy is not recommended, discuss this with a physician before receiving this medicine, best to use some kind, birth control, receiving pegaspargase, tell a physician right away if you think you have become pregnant while receiving pegaspargase, when breast-feeding , because pegaspargase, serious side effects, when breast-feeding , is generally not recommended, receiving it, children infants up to 1 year, safety and efficacy, haven't been established, children 1 year, age and older, has been studied in children 1 year, age and older and has not been shown to cause different side effects, in adults, in fact, the side effects, seem, less severe in children than in adults, there is no specific information comparing the use, pegaspargase, elderly with use in other age groups, safety and efficacy, pegaspargase, elderly, haven't been established, an interaction might occur, change the dose, when you are taking pegaspargase, health care professionals, aspirin, dipyridamole, persantine, heparin, inflammation, pain medicine, except narcotics, warfarin, coumadin, using, together with pegaspargase may increase the risk, bleeding, amphotericin b by injection, fungizone, antithyroid agents, medicine for overactive thyroid, azathioprine, imuran, chloramphenicol, chloromycetin, colchicine, cyclophosphamide, cytoxan, flucytosine, ancobon, ganciclovir, cytovene, interferon, intron a, roferon-a, mercaptopurine, purinethol, methotrexate, mexate, plicamycin, mithracin, zidovudine, azt, retrovir, ever been treated with radiation, cancer medicines, pegaspargase may increase the effects, radiation therapy on the blood other medical problems, pegaspargase, any other medical problems, anticoagulant therapy, treatment with blood thinners, bleeding problems , bleeding, chickenpox, recent exposure, herpes zoster, shingles, risk, severe disease affecting other parts, the body, diabetes mellitus, sugar diabetes, side effects, infection, pegaspargase can decrease my body's ability to fight infection, liver disease , pegaspargase, slower removal, from the body, pancreatitis, side effects, increased, pegaspargase sometimes is given together with certain other medicines, are using a combination, receive each one at the proper time, by mouth, ask my health care professional to help you plan a way, take them at the right times, receiving pegaspargase, drink extra fluids so, will pass more urine, prevent kidney problems and keep my kidneys working well, often causes nausea and vomiting , continue to receive the medicine, begin to feel ill, ask my health care professional for ways, lessen these effects, especially if they are severe, pegaspargase will be different for different patients, the dose that is used may depend on a number, things, the medicine is used for, the patient's size, whether, not other medicines are also being taken, are receiving pegaspargase at home, follow a physician's orders, the directions on the label, any questions about the proper dose, pegaspargase, precautions, know the side effects, a physician check my progress at regular visits to make sure that this medicine is working properly, for unwanted effects, being treated with pegaspargase, after you stop treatment with it, do not have any immunizations, vaccinations, without a physician's approval, pegaspargase may lower my body's resistance and there is a chance you might get the infection the immunization is meant to prevent, other persons living, in my household should not take oral poliovirus vaccine, there is a chance they could pass the poliovirus on, avoid persons who have taken oral poliovirus vaccine, do not get close to them, do not stay, same room with them for long, cannot take these precautions, should consider wearing a protective face mask that covers the nose, mouth, pegaspargase can temporarily lower the number, white blood cells, in my blood, increasing the chance, getting infection, it can also lower the number, platelets, which are necessary for proper blood clotting, there are certain precautions you can take, especially when my blood count is low, to reduce the risk, infection, bleeding, can, avoid people with infection, check with a physician immediately, think you are getting an infection, get a fever, chills, cough, hoarseness, lower back, side pain, painful, difficult urination , check with a physician immediately, notice any unusual bleeding, bruising; black tarry stools , blood in urine , stools, pinpoint red spots on my skin, be careful when using a regular toothbrush, dental floss, toothpick, nurse may recommend other ways to clean my teeth and gums, check with my medical doctor before having any dental work done, do not touch my eyes, the inside, nose unless you have just washed my hands and have not touched anything else, be careful not to cut myself when you are using sharp objects, safety razor, fingernail, toenail cutters, avoid contact sports, other situations where bruising, injury can occur, pegaspargase accidentally seeps out, the vein into which, injected, can damage some tissue and cause scarring, nurse right away if you notice redness, pain, swelling at the place, injection, side effects, along with its needed effects, some unwanted effects, side effects may occur, may need medical attention, side effects occur, abdominal, stomach pain, blurry vision, constipation, dry mouth and skin, fatigue, increased hunger, thirst, increased need to urinate, nausea, skin rash , unexplained weight loss, vomiting, difficulty in breathing, swallowing, hives, itching, hands and feet, reddening, the skin, especially around ears, swelling, eyes, face, inside, nose, unusual tiredness , weakness, sudden and severe, tarry stools , blood in urine , cough, hoarseness, fever, chills, lower back, side pain, painful, difficult urination , pinpoint red spots on skin, unusual bleeding, bruising, side effects may go away during treatment, body adjusts to the medicine, side effects continue, bothersome, general feeling, discomfort, illness, anxiety, behavior change similar to drunkenness, blurred vision , cold sweats, confusion, convulsions, seizures, cool pale skin, difficulty in concentrating, drowsiness , fast heartbeat, headache, appetite, nervousness, nightmares, pain at place, injection, pain in joints, muscles, restless sleep, shakiness, severe, unusual tiredness , weakness, slurred speech, after you stop using this medicine, body may need time to adjust, time this takes depends on the amount, medicine you were using and how long you used it, during this period, time check with a physician if you notice any other side effects not listed above, brand names, oncaspar, another commonly used name is peg- l -asparaginase, category antineoplastic