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tacrolimus, ta-kroe-li-mus, belongs to a group, medicines known as immunosuppressive agents, lower the body's natural immunity in patients who receive organ, kidney, liver, pancreas, lung, heart, transplants, when a patient receives an organ transplant, the body's white blood cells will try to get rid, reject, the transplanted organ, tacrolimus works by preventing the white blood cells from getting rid, the transplanted organ, tacrolimus, other indications, tacrolimus is a very strong medicine, it can cause side effects that can be very serious, kidney problems, can also reduce the body's ability to fight infections, and a physician should talk about the good this medicine will do as well as the risks, using it, tacrolimus, dosage forms, oral, capsules, parenteral, injection, for tacrolimus, allergies tell my health care professional, allergic reaction to tacrolimus, will be receiving this medicine by injection, allergic to any other substances, castor oil, some women have become pregnant and had babies while receiving tacrolimus after an organ transplantation, the newborn babies had temporary kidney problems after birth, some babies were born prematurely, when breast-feeding , tacrolimus passes into breast milk, there is a chance that it causes the same side effects, baby that it does, mother, can be necessary for, stop breast-feeding during treatment, this medicine does not cause different types, side effects, problems in children, in adults, some side effects may occur more, less often than they do in adult patients, there is no specific information comparing the use, tacrolimus, elderly with the use in other age groups, tacrolimus is not expected to cause different side effects, problems in older people, in younger adults, older patients may need lower doses, tacrolimus, an interaction might occur, change the dose, when you are taking tacrolimus, health care professional knows, amiloride, spironolactone, aldactone, triamterene, dyrenium, both tacrolimus and these medicines increase the amount, potassium, potassium levels could become too high, cyclosporine, neoral, may increase the effects, tacrolimus by increasing the amount, kidney problems, danazol, danocrine, erythromycin, medicine for infection, fluconazole, diflucan, itraconazole, sporanox, ketoconazole, nizoral, may increase the effects, tacrolimus by increasing the amount, rifampin, rifadin, may decrease the effects, tacrolimus by decreasing the amount, body other medical problems, tacrolimus, any other medical problems, cancer, tacrolimus can make this condition worse, chickenpox, recent exposure, herpes zoster, shingles, risk, severe disease affecting other parts, the body, diabetes mellitus, sugar diabetes, tacrolimus can increase the amount, sugar, blood, hepatitis, kidney disease , liver disease , other, tacrolimus can have harmful effects on the kidney in patients with these conditions; a lower dose, tacrolimus, needed in patients with these conditions, hyperkalemia, high amount, potassium, blood, nervous system problems, tacrolimus can make these conditions worse, infection, tacrolimus decreases the body's ability to fight infection, take this medicine, don't take less or more, the exact amount, medicine you need has been carefully worked out, taking too much may increase the chance, side effects, while taking too little may lead to rejection, transplanted organ, take my medicine, try to get into the habit, taking it at the same time each day, this will also help tacrolimus work better by keeping a constant amount, blood, absorption, changed if you change my diet, should be taken consistently with respect to meals, should not change the type, amount, food you eat unless you discuss it with my health care professional, do not stop taking this medicine without first checking with a physician, take medicine for the rest, life to prevent my body from rejecting the transplant, tacrolimus will be different for different patients, follow a physician's orders, the directions on the label, the average doses, tacrolimus, dose is different, the number, capsules, take depends on the strength, capsule, dose prescribed by a physician, the number, doses you take each day, the time allowed between doses, time you take the medicine depend on the medical problem for which you are taking tacrolimus, for oral, dosage form, capsules, teenagers, dose is based on body weight, the usual dose is 0.1 to 0.3 milligrams, per kilogram, 0.045 to 0.14 mg per pound, body weight a day, for injection, dosage form, teenagers, dose is based on body weight, the usual dose is 0.03 to 0.05 mg per kg, 0.014 to 0.0227 mg per pound, body weight a day, if i miss a dose, tacrolimus and remember it within 12 hours, take the missed dose, almost time for the next dose, skip the missed dose, go back to my regular dosing schedule, do not double doses, keep out of a child's reach, store away from heat and direct light, in other damp places, do not keep outdated medicine, medicine no longer needed, discarded medicine is out, reach, precautions, know the side effects, the effects, tacrolimus, increased infections and delayed healing, dental work, whenever possible, should be completed prior to beginning this medicine, a physician check my progress at regular visits, do laboratory tests to make sure that tacrolimus is working properly, for unwanted effects, tacrolimus may increase my risk for getting skin cancer when exposed to sunlight, stay out, direct sunlight, especially between the hours, 10:00 am and 3:00 pm if possible, wear protective clothing, a hat, wear sunglasses, apply a sun block product, that has a skin protection factor, spf, 15, higher, questions about this, apply a sunblock lipstick that has an spf, at least 15 to protect my lips, a sun lamp, a tanning bed, notice any unusual changes to my skin, taking tacrolimus, important to maintain good dental hygiene and see a dentist regularly for teeth cleaning, raw oysters, other shellfish may contain bacteria that can cause serious illness, possibly death, this is more likely, a problem if these foods are eaten by patients with certain medical conditions, even eating oysters from "clean" water, good restaurants does not guarantee that the oysters do not contain the bacteria, symptoms, this infection include sudden chills, fever, nausea, vomiting, blood poisoning, sometimes death, eating raw shellfish is not a problem for most healthy people, patients with the following conditions, at greater risk: cancer, immune disorders, organ transplantation, long-term corticosteroid use, as for asthma, arthritis, organ transplantation, liver disease , viral hepatitis, excess alcohol intake, 2 to 3 drinks, more per day, diabetes, stomach problems, previous stomach surgery and low stomach acid, hemochromatosis, an iron disorder, do not eat raw oysters, other shellfish, taking tacrolimus, be sure oysters and shellfish are fully cooked, being treated with tacrolimus, after you stop treatment with it, important to see a physician about the immunizations, vaccinations, should receive, do not get any immunizations without a physician's approval, tacrolimus lowers my body's resistance, for some immunizations, there is a chance you might get the infection the immunization is meant to prevent, for other immunizations, can be especially important to receive the immunization to prevent a disease, other persons living, in my house should not take oral poliovirus vaccine since there is a chance they could pass the poliovirus on, avoid persons who have recently taken oral poliovirus vaccine, do not get close to them, do not stay, same room with them for very long, cannot take these precautions, should consider wearing a protective face mask that covers the nose and mouth, treatment with tacrolimus may also increase the chance, getting other infections, can, avoid people with colds, other infections, think you are getting a cold, other infection, tacrolimus is not available in all countries, are traveling to another country, be sure you will have a supply, grapefruits and grapefruit juice may increase the effects, tacrolimus by increasing the amount, should not eat grapefruit, drink grapefruit juice, side effects, along with its needed effects, some unwanted effects, some side effects will have signs, symptoms, can see, feel, a physician will watch for others by doing certain tests, the way tacrolimus acts on the body, there is a chance that it, effects that may not occur until years after the medicine is used, delayed effects may include certain types, cancer, lymphomas, skin cancers, nurse immediately, side effects occur, abdominal pain , abnormal dreams, agitation, anxiety, chills, confusion, convulsions, seizures, diarrhea, dizziness , fever and sore throat, flu-like symptoms, frequent urination, hallucinations, seeing, hearing things that are not there, headache, infection, itching, appetite, energy, weakness, mental depression, muscle trembling, twitching, nausea, nervousness, pale skin, shortness of breath, skin rash , swelling, feet, lower legs, tingling, trembling and shaking, hands, trouble in sleeping, unusual bleeding, bruising, unusual tiredness , weakness, vomiting, blurred vision , chest pain , increased sensitivity to pain, muscle cramps , numbness , pain in legs, ringing in ears, sweating, enlarged heart, flushing, face, neck, general feeling, discomfort, illness, weight loss, wheezing, incidence not determined--—observed during clinical practice with tacrolimus; estimates, frequency cannot be determined, tarry, stools, blistering, peeling, loosening, skin, bloating, blood in urine , blurred vision , cough, constipation, cramping, burning, convulsions, drowsiness , fainting, fast, slow, irregular heartbeat , heartburn, increased blood pressure, increased thirst, indigestion, irregular heartbeat , itching, joint, muscle pain, lightheadedness, appetite, lower back/side pain, nausea, pinpoint red spots on skin, pounding, rapid pulse, recurrent fainting, red irritated eyes, red skin lesions, often with a purple center, shortness of breath, sores, stomach pain, sugar, urine, troubled breathing, ulcers, white spots in mouth, lips, weakness, weight gain, yellow eyes, skin, may also cause the following side effects that a physician will watch for, hyperkalemia, too much potassium, blood, hypomagnesemia, not enough magnesium, blood, kidney problems, hyperlipidemia, high cholesterol, hypertension, high blood pressure , other side effects, additional information once a medicine has been approved for marketing for a certain use, experience may show, also useful for other medical problems, not specifically included, product labeling, tacrolimus is used in certain patients with the following medical conditions, bone marrow transplantation, uveitis, severe, refractory, an eye condition, for patients receiving bone marrow transplantation, tacrolimus may work by preventing the cells from the transplanted bone marrow from attacking the cells, the patient, tacrolimus for patients receiving bone marrow transplantation is based on body weight, the usual dose is 0.12 to 0.3 mg per kg, 0.05 to 0.14 mg per pound, body weight a day for patients taking tacrolimus by mouth, 0.04 to 0.1 mg per kg, 0.018 to 0.045 mg per pound, body weight a day for patients receiving tacrolimus by injection, tacrolimus for patients with severe, refractory uveitis is based on body weight, for severe, refractory uveitis, the usual dose is 0.1 to 0.15 mg per kg, 0.045 to 0.068 mg per pound, body weight a day, other than, information, there is no additional information relating to, side effects for these uses, brand names, prograf, prograf, category immunosuppressant