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filgrastim and sargramostim are synthetic, man-made, versions, substances naturally produced, in my body, substances, colony stimulating factors, help the bone marrow to make new white blood cells, when certain cancer medicines fight my cancer cells, also affect those white blood cells that fight infection, to help prevent infections when these cancer medicines are used, colony stimulating factors, colony stimulating factors also, help the bone marrow recover after bone marrow transplantation and stem cell transplantation, colony stimulating factors are available only with a physician's prescription, dosage form parenteral, filgrastim, injection, sargramostim, injection, for colony stimulating factors, allergic reaction to the colony stimulating factor, allergic to any other substances, foods, preservatives, dyes, colony stimulating factors, haven't been studied in pregnant women, before you take a colony stimulating factor, pregnant, may become pregnant, filgrastim, in studies in rabbits, filgrastim did not cause birth defects , did cause internal defects, a decrease in average weight, the fetus at high doses, sargramostim, studies, birth defects , haven't been done in animals, when breast-feeding , not known whether colony stimulating factors pass into human breast milk, not been reported to cause problems in nursing babies, mothers, taking a colony stimulating factor and who wish to breast-feed, children although, colony stimulating factors in children with use in other age groups, is not expected to cause different side effects, problems in children, in adults, data from clinical trials in children indicate that the safety, filgrastim is similar in both adults and children receiving certain cancer medicines, sargramostim may contain benzyl alcohol and should not be given to infants because it could cause serious adverse effects, haven't been studied specifically in older people, colony stimulating factors, elderly with use in other age groups, has been used in many elderly patients and is not expected to cause different side effects, problems in older people, in younger adults, an interaction might occur, change the dose, when you are taking a colony stimulating factor, health care professional knows, chemotherapy, radiation therapy, should not use filgrastim close to the time you are undergoing chemotherapy, radiation therapy for cancer treatment, other medical problems, colony stimulating factors, any other medical problems, conditions caused by inflammation, immune system problems, there is a chance these, worsened by colony stimulating factor, heart disease , risk, some unwanted effects, heart rhythm problems, retaining water, kidney disease , liver disease , may sometimes be worsened by colony stimulating factor, leukemia, cancer, the blood-forming organs, may make condition worse, lung disease, colony stimulating factor, shortness of breath, sickle cell disease, condition that affects the cells, in my blood, may make condition worse, injecting this medicine myself , use it exactly as directed by a physician, it more often, the exact amount, medicine you need has been carefully worked out, using too much will increase the risk, side effects, while using too little may not improve my condition, are injecting this medicine myself , each package, colony stimulating factor will contain a patient instruction sheet, read this sheet carefully and make sure you understand, prepare the injection, disposable syringes, give the injection, how long the injection is stable, any questions about, this, colony stimulating factors will be different for different patients, the dose that is used may depend on a number, things, the medicine is being used for, the patient's body weight, size, whether, not other medicines are also being taken, are receiving colony stimulating factors at home, follow a physician's orders, the directions on the label, any questions about the proper dose, colony stimulating factors, if i miss a dose, keep out of a child's reach, store in a refrigerator, keep the medicine from freezing, do not keep outdated medicine, medicine no longer needed, ask my doctor how to get rid, any medicine you do not use, discarded medicine is out of a child's reach, precautions, know the side effects, a physician check my progress at regular visits to make sure that this medicine is working properly, for unwanted effects, colony stimulating factors, prevent, reduce the risk, infection, being treated with cancer medicines, body's ability to fight infection is reduced, call a physician at the first sign, any infection, get a fever, chills, start antibiotic treatment, contact a physician if you develop shortness, breath, tightness in chest, troubled breathing, wheezing, could be symptoms, a serious lung condition, adult respiratory distress syndrome, ards, experience left upper abdominal, shoulder tip pain, contact a physician, could be symptoms, an enlarged, ruptured spleen, colony stimulating factors commonly cause mild bone pain, usually, lower back, pelvis, about the time the white blood cells start to come back, in my bone marrow, the pain is usually mild and lasts only a few days, prescribe a mild analgesic, painkiller, for, take during that time, find that the analgesic is not strong enough, talk with a physician about using something that will make you more comfortable, side effects, along with its needed effects, some unwanted effects, side effects may occur, may need medical attention, the side effects listed below include only those that might be caused by colony stimulating factors, to find out about other side effects, caused by the cancer medicines you are also receiving, look under the information about those specific medicines, side effects occur, for filgrastim, redness, pain at the site, subcutaneous, under the skin, injection, fever, rapid, irregular heartbeat , sores on skin, wheezing, for sargramostim, fever, redness, pain at the site, subcutaneous, under the skin, injection, shortness of breath, swelling, feet, lower legs, weight gain, chest pain , rapid, irregular heartbeat , sores on skin, wheezing, side effects may go away during treatment, body adjusts to the medicine, side effects continue, bothersome, for both filgrastim and sargramostim, headache, pain in arms, legs, pain in joints, muscles, pain in lower back, pelvis, skin rash , itching, for sargramostin only, in addition to, dizziness , faintness after first dose, flushing, face after first dose, weakness, other side effects, additional information once a medicine has been approved for marketing for a certain use, experience may show that it also is useful for other medical problems, not specifically included, product labeling, colony stimulating factors are used in certain patients with the following medical conditions, failure, delay, myeloid engraftment after hemapoietic stem cell transplantation, myelodysplastic syndromes, neutropenia, aids-associated, neutropenia, drug-induced other than, information, there is no additional information relating to, side effects for these uses, brand names some commonly used brand names are, neupogen, leukine, for quick reference, colony stimulating factors are numbered to match the corresponding brand names,  granulocyte colony stimulating factor, g-csf,  granulocyte-macrophage colony stimulating factor, gm-csf, this information applies to the following medicines filgrastim, fil-gra-stim, sargramostim, sar-gram-oh-stim,