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histamine h ₂-receptor antagonists, also known as h ₂-blockers, treat duodenal ulcers and prevent their return, treat gastric ulcers and for some conditions, zollinger-ellison disease, in which the stomach produces too much acid, in over-the-counter, otc, strengths, relieve and/or prevent heartburn, acid indigestion , sour stomach , h ₂-blockers, h ₂-blockers work by decreasing the amount, acid produced by the stomach, available, following dosage forms, oral, cimetidine, oral solution, tablets, famotidine, oral suspension, tablets, chewable tablets, oral disintegrating tablets, nizatidine, capsules, tablets, ranitidine, syrup, tablets, effervescent tablets, parenteral, cimetidine, injection, famotidine, injection, ranitidine, injection, for h ₂-blockers, allergic reaction to cimetidine, famotidine, nizatidine, ranitidine, h ₂-blockers, haven't been studied in pregnant women, in animal studies, famotidine and ranitidine, haven't been shown to cause birth defects , one study in rats suggested that cimetidine may affect male sexual development, more studies, needed to confirm this, studies in rabbits with very high doses, nizatidine causes miscarriages and low birth weights, pregnant, may become pregnant before taking h ₂-blockers, when breast-feeding , cimetidine, famotidine, nizatidine, ranitidine pass into the breast milk, known to cause, unwanted effects, decreased amount, stomach acid and increased excitement, nursing baby, can be necessary for, take another medicine, to stop breast-feeding during treatment, be sure you have discussed the risks and benefits, the medicine with a physician, this medicine has been tested in children, in effective doses, has not been shown to cause different side effects, in adults when used for short periods, confusion and dizziness , especially likely to occur in elderly patients, usually more sensitive than younger adults to the effects, h ₂-blockers, an interaction might occur, change the dose, when you are taking, receiving h ₂-blockers, health care professionals, aminophylline, somophyllin, anticoagulants, blood thinners, caffeine, nodoz, metoprolol, lopressor, oxtriphylline, choledyl, phenytoin, dilantin, propranolol, inderal, theophylline, somophyllin-t, tricyclic antidepressants, amitriptyline, elavil, amoxapine, asendin, clomipramine, anafranil, desipramine, pertofrane, doxepin, sinequan, imipramine, tofranil, nortriptyline, aventyl, protriptyline, vivactil, trimipramine, surmontil, with cimetidine has been shown to increase the effects, cimetidine, this is less, a problem with ranitidine and has not been reported for famotidine, nizatidine, all, the h ₂-blockers are similar, so drug interactions may occur with, itraconazole, sporanox, ketoconazole, nizoral, h ₂-blockers may decrease the effects, itraconazole, ketoconazole; h ₂-blockers should be taken at least 2 hours after these medicines other medical problems, h ₂-blockers, any other medical problems, kidney disease , liver disease , the h ₂-blocker may build up, bloodstream, which may increase the risk, side effects, phenylketonuria, pku, some h ₂-blockers contain aspartame, aspartame is converted to phenylalanine, used with caution in patients with pku, the pepcid ac brand, famotidine chewable tablets contains 1.4 mg, phenylalanine per 10-mg dose, the pepcid rpd brand, famotidine oral dispersible tablets contains 1.05 mg, phenylalanine per 20-mg dose, the zantac brand, ranitidine efferdose tablets contain 2.81 mg, phenylalanine per 25-mg dose and 16.84 mg, phenylalanine per 150-mg dose, porphyria, rare family disease that affects the way my body digests food, may make condition worse in patients who have acute porphyria, weakened immune system, difficulty fighting infection, decrease in stomach acid caused by h ₂-blockers may increase the possibility, a certain type, infection, for patients taking the nonprescription strengths, for heartburn, acid indigestion , sour stomach , do not take the maximum daily dosage continuously for more than 2 weeks, directed to do so by a physician, trouble in swallowing, persistent abdominal pain , see a physician promptly, a serious condition that may need different treatment, for patients taking the prescription strengths, for more serious problems, one dose a day, take it at bedtime, otherwise directed, two doses a day, take one, morning and one at bedtime, several doses a day, take them with meals and at bedtime for best results, can take several days before this medicine begins to relieve stomach pain, to help relieve this pain, antacids, taken with the h ₂-blocker, a physician has told you not to use them, should wait one-half to one hour between taking the antacid, h ₂-blocker, medicine for the full time, begin to feel better, keep my appointments with a physician for check-ups so that a physician will be better able to tell you when to stop taking this medicine, for patients taking famotidine chewable tablets, chew the tablets well before swallowing, for patients taking famotidine oral disintegrating tablets, make sure my hands are dry, leave tablets in unopened package until the time, then open the pack and remove the tablet, immediately place the tablet on the tongue, the tablet will dissolve in seconds, may swallow it with my saliva, do not need to drink water, other liquid to swallow the tablet, for patients taking ranitidine effervescent tablets, remove the foil wrapping and dissolve the dose in 6 to 8 ounces, water before drinking, do not chew, swallow whole, dissolve on the tongue, the amount you should give to my infant is, measured with the specially marked dropper, oral syringe, unsure how much medicine to give my infant, histamine h ₂-receptor antagonists, h ₂-blockers, will be different for different patients, follow a physician's orders, the directions on the label, the average doses, dose is different, the number, capsules, tablets, teaspoonfuls, solution, suspension, syrup, take depends on the strength, the number, doses you take each day, the time allowed between doses, time you take the medicine depend on the medical problem for which you are taking the h, for cimetidine, for oral, dosage forms, solution and tablets, to treat duodenal, gastric ulcers, teenagers, 300 milligrams, four times a day, with meals and at bedtime, some people may take 400, 600 mg two times a day, waking up and at bedtime, others may take 800 mg at bedtime, 20 to 40 mg per kilogram, 9.1 to 18.2 mg per pound, body weight a day, divided into four doses, taken with meals and at bedtime, to prevent duodenal ulcers, teenagers, 300 mg two times a day, waking up and at bedtime, instead some people may take 400 mg at bedtime, dose, to treat heartburn, acid indigestion , sour stomach , adults and teenagers, 100 to 200 mg with water when symptoms start, repeated once in twenty-four hours, do not take more than 400 mg in twenty-four hours, dose, to prevent heartburn, acid indigestion , sour stomach , adults and teenagers, 100 to 200 mg with water up to one hour before eating food, drinking beverages you expect to cause symptoms, do not take more than 400 mg in twenty-four hours, dose, to treat conditions in which the stomach produces too much acid, 300 mg four times a day, with meals and at bedtime, a physician may change the dose, dose, to treat gastroesophageal reflux disease, 800 to 1600 mg a day, divided into smaller doses, treatment usually lasts for 12 weeks, dose, for injectable, dosage form, to treat duodenal ulcers, gastric ulcers, conditions in which the stomach produces too much acid, teenagers, 300 mg injected into muscle, every six to eight hours, 300 mg injected slowly into a vein every six to eight hours, 900 mg, injected slowly into a vein around the clock at the rate, 37.5 mg per hour, some people may need 150 mg at, before beginning the around-the-clock treatment, 5 to 10 mg per kg, 2.3 to 4.5 mg per pound, body weight injected into a vein, muscle, every six to eight hours, to prevent stress-related bleeding, teenagers, 50 mg per hour injected slowly into a vein around the clock for up to 7 days, dose, for famotidine, for oral, dosage forms, suspension, tablets, chewable tablets, oral disintegrating tablets, to treat duodenal ulcers, teenagers, 40 milligrams, once a day at bedtime, some people may take 20 mg two times day, dose, to prevent duodenal ulcers, teenagers, 20 mg once a day at bedtime, dose, to treat gastric ulcers, teenagers, 40 mg once a day at bedtime, dose, to treat heartburn, acid indigestion , sour stomach , adults and teenagers, 10 mg with water when symptoms start, repeated once in twenty-four hours, do not take more than 20 mg in twenty-four hours, dose, to prevent heartburn, acid indigestion , sour stomach , adults and teenagers, 10 mg taken one hour before eating a meal you expect to cause symptoms, repeated once in twenty-four hours, do not take more than 20 mg in twenty-four hours, dose, to treat conditions in which the stomach produces too much acid, 20 mg every six hours, a physician may change the dose, dose, to treat gastroesophageal reflux disease, teenagers, 20 mg two times a day, usually for up to 6 weeks, children weighing more than 10 kg, 22 pounds, 1 to 2 mg per kilogram, 0.5 to 0.9 mg per pound, body weight a day divided into two doses, children weighing less than 10 kg, 22 pounds, 1 to 2 mg per kg, 0.5 to 0.9 mg per pound, body weight a day, divided into three doses, for injectable, dosage form, to treat duodenal ulcers, gastric ulcers, conditions in which the stomach produces too much acid, teenagers, 20 mg injected into a vein, every twelve hours, dose, for nizatidine, for oral, dosage forms, capsules and tablets, to treat duodenal, gastric ulcers, teenagers, 300 milligrams, once a day at bedtime, some people may take 150 mg two times a day, dose, to prevent duodenal ulcers, adults and teenagers, 150 mg once a day at bedtime, dose, to prevent heartburn, acid indigestion , sour stomach , adults and teenagers, 75 mg taken thirty to sixty minutes before eating a meal you expect to cause symptoms, repeated once in twenty-four hours, dose, to treat gastroesophageal reflux disease, adults and teenagers, 150 mg two times a day, dose, for ranitidine, for oral, dosage forms, syrup, tablets, effervescent tablets, to treat duodenal ulcers, teenagers, 150 milligrams, two times a day, some people may take 300 mg once a day at bedtime, 2 to 4 mg per kilogram, 1 to 2 mg per pound, body weight per day, usually given as two divided doses, total dose will not be more than 300 mg a day, to prevent duodenal ulcers, teenagers, 150 mg at bedtime, dose, to treat gastric ulcers, teenagers, 150 mg two times a day, 2 to 4 mg per kilogram, 1 to 2 mg per pound, body weight per day, usually given as two divided doses, total dose will not be more than 300 mg a day, to treat heartburn, acid indigestion , sour stomach , adults and teenagers, 150 mg with water when symptoms start, repeated once in twenty-four hours, do not take more than 300 mg in twenty-four hours, dose, to prevent heartburn, acid indigestion , sour stomach , adults and teenagers, 150 mg with water taken thirty to sixty minutes before eating a meal, drinking beverages you expect to cause symptoms, do not take more than 300 mg in twenty-four hours, dose, to treat some conditions in which the stomach produces too much acid, teenagers, 150 mg two times a day, a physician may change the dose, dose, to treat gastroesophageal reflux disease, teenagers, 150 mg two times a day, dose, 5 to 10 mg per kg, 2.3 to 4.6 mg per pound, body weight a day, usually divided and given in two doses during the day, most children usually will not take more than 300 mg a day, for injectable, dosage form, to treat duodenal ulcers, gastric ulcers, conditions in which the stomach produces too much acid, teenagers, 50 mg injected into a muscle every six to eight hours, 50 mg injected slowly into a vein every six to eight hours, may receive 6.25 mg per hour injected slowly into a vein around the clock, most people will usually not need more than 400 mg a day, to treat duodenal, gastric ulcers, 2 to 4 mg per kg, 1 to 2 mg per pound, body weight a day, injected slowly into a vein, if i miss a dose, almost time for my next dose, skip the missed dose, back to my regular dosing schedule, do not double doses, keep out of a child's reach, store away from heat and direct light, do not store the capsule, tablet form, in other damp places, heat, moisture, the medicine to break down, keep the liquid form, from freezing, do not keep outdated medicine, medicine no longer needed, discarded medicine is out of a child's reach, precautions, know the side effects, some tests, affected by this medicine, taking this medicine before, have any skin tests for allergies, have any tests to determine how much acid my stomach produces, remember that certain medicines, aspirin, certain foods and drinks, citrus products, carbonated drinks, etc, irritate the stomach, problem worse, cigarette smoking tends to decrease the effect, h ₂-blockers by increasing the amount, acid produced by the stomach, this is more likely to affect the stomach's nighttime production, acid, while taking h ₂-blockers, stop smoking completely, at least do not smoke after taking the last dose, the day, drinking alcoholic beverages while taking an h ₂-receptor antagonist has been reported to increase the blood levels, alcohol, should consult my health care professional for guidance, check with a physician if my ulcer pain continues, gets worse, side effects, along with its needed effects, some unwanted effects, side effects may occur, may need medical attention, side effects occur, abdominal pain , back, leg, stomach pain, bleeding, crusting sores on lips, blistering, burning, redness, scaling, tenderness, skin, blisters on palms, hands and soles, feet, changes in vision, blurred vision , confusion, coughing, difficulty in swallowing, dark-colored urine, dizziness , fainting, fast pounding, irregular heartbeat , fever and/or chills, flu-like symptoms, general feeling, discomfort, illness, hives, inflammation, blood vessels, joint pain, light-colored stools, mood, mental changes, anxiety, agitation, confusion, hallucinations, seeing, hearing, feeling things that are not there, mental depression, nervousness, severe mental illness, muscle cramps , aches, nausea, vomiting, appetite, pain, peeling, sloughing, skin, red, irritated eyes, shortness of breath, skin rash , itching, slow heartbeat, sore throat, sores, ulcers, white spots on lips, in mouth, genitals, sudden difficult breathing, swelling, face, lips, mouth, tongue, eyelids, swelling, hands, feet, swollen, painful glands, tightness in chest, troubled breathing, unusual bleeding, bruising, unusual tiredness , weakness, unusually slow, irregular breathing, wheezing, yellow eyes, skin, side effects may go away during treatment, body adjusts to the medicine, side effects continue, bothersome, constipation, decreased sexual ability, especially in patients with zollinger-ellison disease who have received high doses, cimetidine for at least 1 year, decrease in sexual desire, diarrhea, difficult urination , dizziness , drowsiness , dryness, mouth, skin, headache, decreased urination, increased sweating, hair, ringing, buzzing in ears, runny nose, swelling, breasts, breast soreness in females and males, trouble in sleeping, the side effects listed above, reported for each, reported for at least one, all, the h ₂-blockers are similar, side effects may occur with, other side effects, additional information once a medicine has been approved for marketing for a certain use, experience may show, also useful for other medical problems, uses are not included in product labeling, h ₂-blockers are used in certain patients with the following medical conditions, damage to the stomach and/or intestines due to stress, trauma, hives, pancreatic problems, stomach, intestinal ulcers, sores, resulting from damage caused by medication, treat rheumatoid arthritis other than, information, there is no additional information relating to, side effects for these uses, brand names some commonly used brand names are, axid, axid ar, fluxid, mylanta ar acid reducer, pepcid, pepcid i.v, pepcid ac acid controller, pepcid rpd, tagamet, tagamet hb, zantac, zantac 150, zantac 300, zantac 25 efferdose tablets, zantac 150 efferdose tablets, act, apo-cimetidine, apo-famotidine, apo-nizatidine, apo-ranitidine, axid, dyspep hb, gen-cimetidine, gen-famotidine, gen-ranitidine, maalox h2 acid controller, novo-cimetine, novo-famotidine, novo-ranitidine, nu-cimet, nu-famotidine, nu-ranit, pepcid, pepcid ac, pepcid i.v, peptol, pms-cimetidine, tagamet, ulcidine, ulcidine-hb, zantac, zantac 75,