| Betterchem |

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| FDA approval activities
for this prescription drug:
Alphagan (brimonidine tartrate ophthalmic solution), 0.5, 0.2 & (P) 0.15%, Allergan NDA 20-490/S7, 20-613/S18 & 21-262/S6 12/20/01 6/19/02 6/19/02 6/19/02 Alphagan P (brimonidine tartrate ophthalmic solution), 0.15%, Allergan NDA 21-262 Brimonidine Tartrate Ophthalmic Solution, 0.2%, Bausch & Lomb ANDA 76-260 5/28/03 Brimonidine Tartrate Ophthalmic Solution, 0.2%, Alcon ANDA 76-254 9/16/03 Brimonidine Tartrate Ophthalmic Solution, 0.2%, Tentatively Approved Alcon Universal, Ltd. ANDA 76-254 |
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